White paper published at ICASA 2013
Randomized Controlled Study Comparing Odor Levels When Using 3 Different Hygiene Techniques While Wearing PrePex
A concern raised by WHO TAG consulting members regarding a potential side effect while wearing the PrePex is some level of odor extraction from the foreskin. PrePex researchers from Rwanda have assumed that there is a possible relation between the level of odor to the personal hygiene and foreskin daily washing technique. The main objective was to compare different odor levels when examining three arms with identical personal hygiene but different foreskin hygiene techniques.
Group 1 was instructed to clean the foreskin with soapy water three times a day using a syringe.
Group 2 was instructed to clean the foreskin with diluted chlorhexidine (1%) once a day using a syringe.
Group 3 – a control group – is following current hygiene instructions which includes standard washing in a shower.
101 subjects were enrolled to the study and randomly allocated into 3 study groups – 32 for group 1, 32 for group 2 and 37 for group 3.
The study results clearly demonstrate that there is a statistically significant reduction of odor when using Chlorhexidine compared to soapy water and to control arm. The results demonstrated that odor from the foreskin while wearing the PrePex device results directly from the type and technique of foreskin hygiene and is not related to the necrotizing foreskin or to the device.